Leptin antibody

Catalog No. ABIN1169150

The Rabbit Polyclonal anti-Leptin antibody is suitable to detect Leptin in samples from Rat. It has been validated for WB and ELISA.

Quick Overview for Leptin antibody (ABIN1169150)

Target: Leptin (LEP)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leptin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Leptin Antibody

Purpose: anti-Leptin (rat), pAb

Specificity: Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot.

Cross-Reactivity (Details): Weakly cross-reacts with human and mouse leptin.

Characteristics: Polyclonal Antibody. Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.

Sterility: 0.2 μm filtered

Immunogen: Recombinant rat leptin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for Leptin

Target: Leptin (LEP)

Alternative Name: Leptin

Background:

Alternate Names/Synonyms: OB Gene Product, Obese Factor

Product Description: Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.

UniProt: P50596

Pathways: JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process