Prednisolone antibody
Reactivity: Hormone
IAC, IA
Host: Sheep
Polyclonal
unconjugated
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- Target
- Prednisolone
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Reactivity
- Hormone
-
Host
-
Sheep
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Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
- Application
- Immunoaffinity Chromatography (IAC), Immunoassay (IA)
- Sensitivity
-
10ng/mL
Prednisolone produces 59% inhibition in a competitive ELISA employing Prednisolone polyclonal Antibody - Characteristics
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Polyclonal
High sensitivity
High concentration
Excellent specificity to target compound
Detailed cross reactivity profiles
Available for bulk purchase
Stable when stored at -20 °C
Excellent reproducibility between lot numbers
Matching conjugates available - Immunogen
- Prednisolone-BTG
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- Application Notes
- The antibody is suitable for the development of immunoassays or immunoaffinity purification columns.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 15.88 mg/mL
- Buffer
- 20 mM Phosphate, 150 mM Sodium Chloride
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- Prednisolone
- Target Type
- Hormone
- Background
- Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS) [1]. DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver [2]. DHEA in adults is present at plasma concentrations 100 to 500 times higher than those of testosterone. DHEA can be metabolized to androgens and/or estrogens in the prostate [3]. Hepatic metabolites include 16alpha-hydroxy-DHEA, 7alpha-hydroxy-DHEA, and 7-oxo-DHEA [4]. 7beta-OH-DHEA is a metabolite [5]. The major metabolite produced in humans is a mono-hydroxylated DHEA species [4]. Synthesis of a 7alpha-hydroxy-DHEA and 5-androstene-3beta, 17beta-diol occurs in the frontal cortex, hippocampus, aμgdala, cerebellum and striatum [6].
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