CCR5 antibody (FITC)

Catalog No. ABIN119676

Product Details anti-CCR5 Antibody (FITC)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CCR5 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises the CD195 cell surface antigen, a 45 kDa glycoprotein also known as CCR5.

Purification: Affinity chromatography on Protein G

Immunogen: CHO cells transfected with human CCR5. Spleen cells from immunised rats were fused with cell of the rat Y3 myeloma cell line.

Clone: HEK-1-85a

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 100 μL fresh whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Alternative Name: CD195 / CCR5 (CCR5 Products)

Synonyms: CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody

Background: CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also serves as a coreceptor or the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor

Gene ID: 1234

NCBI Accession: NP_000570

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size