For best experience we recommend to activate Javascript in your browser.

CD8 antibody (PE)

CD8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-31 PE

Catalog No. ABIN120697

Datasheet as PDF

Target See all CD8 Antibodies

CD8
Reactivity
220

72

26

12

12

11

9

9

9

9

8

7

7

6

6

6

5

5

5

3

3

2

2
Human
Host
224

53

39
Mouse
Compatible Secondaries
Clonality
260

47

2
Monoclonal
Conjugate
92

39

31

23

11

8

6

6

6

5

5

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD8 antibody is conjugated to PE
Application
265

64

63

44

42

42

30

19

17

14

14

14

8

5

4

3

1

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

The antibody recognizes a conformationally-dependent epitope of CD8 antigen.

Characteristics

Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain

Immunogen

Crude thymus membrane fraction.

Clone

MEM-31

Isotype

IgG2a

Top Product

Discover our top product CD8 Primary Antibody
anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reactivity: Human, Mouse, Rat FACS, IHC (fro), WB, ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD8 (CD8) antibody (PE)
CD8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-31 PE

anti-CD8 (CD8) (AA 22-187) antibody
CD8 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD8 (CD8) antibody
CD8 Reactivity: Human FACS, IP, CyTOF Host: Mouse Monoclonal MEM-31 unconjugated

anti-CD8 (CD8) antibody (PE)
CD8 Reactivity: Cat FACS Host: Mouse Monoclonal fCD8 PE

anti-CD8 (CD8) antibody
CD8 Reactivity: Human IHC, WB, IP, ELISA Host: Rabbit Monoclonal 3C3 unconjugated Recombinant Antibody

anti-CD8 (CD8) antibody (Biotin)
CD8 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-31 Biotin

anti-CD8 (CD8) antibody (FITC)
CD8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-31 FITC

anti-CD8 (CD8) antibody (PerCP)
CD8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-31 PerCP

anti-CD8 (CD8) antibody (APC)
CD8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-31 APC

Application Notes

Flow Cytometry analysis of human blood cells using 20 l reagent / 100 l whole blood or10^6 cells in a suspension. Does not work in Immunohistocchemistry omn paraffin sections or Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

0.1 mg/mL

Storage

4 °C

Storage Comment

Store at 2-8 °C. Do not freeze. Avoid prolonged exposure to light.
Shelf life: one year fromdespatch.

Expiry Date

12 months
Target

CD8

Alternative Name

CD8 (CD8 Products)

Synonyms

CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody

Background

The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as ab heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as aa homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8b level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 a-b but not a-a dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Gene ID

925

UniProt

P01732