TAS1R1 antibody (N-Term)

Catalog No. ABIN122265

Product Details anti-TAS1R1 Antibody

Target: TAS1R1 (Taste Receptor, Type 1, Member 1 (TAS1R1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS1R1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with TAS1R1 (Family: GPCR, Subfamily: Taste).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Peptide Immunogen Affinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for TAS1R1

Target: TAS1R1 (Taste Receptor, Type 1, Member 1 (TAS1R1))

Alternative Name: TAS1R1 / GPR70 (TAS1R1 Products)

Synonyms: GPR70 antibody, T1R1 antibody, TR1 antibody, Gpr70 antibody, T1r1 antibody, taste receptor, type 1, member 1 antibody, taste 1 receptor member 1 antibody, tas1r1 antibody, TAS1R1 antibody, Tas1r1 antibody

Background: TAS1R1 is a Taste Receptor, G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene. The expression of this gene is largely restricted to taste buds in mammals. However, some ESTs have been isolated from liver, testis and bone. TAS1R1 combines with TAS1R3 to function as an L-amino-acid receptor and is only activated by these sweet amino acids. ESTs have been isolated from testis libraries.Synonyms: G-protein coupled receptor 70, GM148, TR1, Taste receptor T1R1, Taste receptor type 1 member 1

Gene ID: 80835

UniProt: Q7RTX1