RNF2 antibody (AA 189-201)

Catalog No. ABIN129557

Product Details anti-RNF2 Antibody

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Binding Specificity: AA 189-201

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: RING1B Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 189-201 of human RING1B protein.

Isotype: IgG

Application Details

Application Notes: Anti-RING1B purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 38 kDa in size corresponding to RING1B by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RING1B (RNF2 Products)

Synonyms: BAP-1 antibody, BAP1 antibody, DING antibody, HIPI3 antibody, RING1B antibody, RING2 antibody, AI326319 antibody, AI450156 antibody, AU019207 antibody, Ring1B antibody, dinG antibody, fa19h05 antibody, ring1b antibody, wu:fa19h05 antibody, wz4556 antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring2 antibody, ring finger protein 2 antibody, ring finger protein 2 L homeolog antibody, RNF2 antibody, Rnf2 antibody, rnf2 antibody, rnf2.L antibody

Background: RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins.  The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.
Synonyms: BAP1 antibody, DING antibody, DinG protein antibody, RING finger protein BAP1 antibody, E3 ubiquitin protein ligase RING 2 antibody, Huntingtin interacting protein 2 interacting protein 3 antibody, RNF 2 antibody

Gene ID: 6045, 6005747

UniProt: Q99496