JAG2 antibody (AA 111-128)

Catalog No. ABIN129632

Product Details anti-JAG2 Antibody

Target: JAG2 (Jagged 2 (JAG2))

Binding Specificity: AA 111-128

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged-2. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. Swiss Prot accession Q9QYE5. Expected to cross-react with rat Jagged-2.

Isotype: IgG

Application Details

Application Notes: Anti-Jagged-2 Antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays including western blot, immunohistochemistry, and immunofluorescence is expected.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: Jagged-2 (JAG2 Products)

Synonyms: D12Ggc2e antibody, Serh antibody, mJagged2-1 antibody, sm antibody, HJ2 antibody, SER2 antibody, jag2 antibody, serB antibody, zgc:152855 antibody, jagged 2 antibody, jagged 2b antibody, JAG2 antibody, jag2 antibody, Jag2 antibody, jag2b antibody

Background: Jagged 2 antibdody detect the Jagged protein. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. Anti-Jagged 2 antibody is ideal for investigators involved in developmental biology research.
Synonyms: D12Ggc2e antibody, HJ 2 antibody, HJ2 antibody, JAG 2 antibody, JAG2 antibody, Jagged 2 precursor antibody, Jagged2 antibody, Syndactylism antibody, Protein jagged-2, SER2, hJ2

Gene ID: 3714

UniProt: Q9QYE5

Pathways: Notch Signaling, Sensory Perception of Sound