IL-1 beta antibody

Catalog No. ABIN1383938

There are 2+ publications for this product available. The Mouse Monoclonal anti-IL-1 beta antibody is suitable to detect IL-1 beta in samples from Human. It has been validated for ELISA, FACS, Func and ELISpot.

Quick Overview for IL-1 beta antibody (ABIN1383938)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Functional Studies (Func), ELISpot

Clone: B-A15

Product Details anti-IL-1 beta Antibody

Specificity: Recognises both natural (pro and mature) and recombinant human IL-1b

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant antibody from the original clone,Recombinant human IL-1b

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IL-1β induced proliferation on D10S murine cell line

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store at +2-8°C for 12 months. DO NOT FREEZE.

References for anti-IL-1 beta antibody (ABIN1383938)

Ikoma, Nomura, Ito, Katsumata, Nakata, Iwanaga, Okada, Kikkawa, Tamakoshi, Nagasaka, Tsujimoto, Mizutani: "Interleukin-1beta stimulates placental leucine aminopeptidase/oxytocinase expression in BeWo choriocarcinoma cells." in: Molecular human reproduction, Vol. 9, Issue 2, pp. 103-10, (2003) (PubMed).

Chêne, Nugeyre, Barré-Sinoussi, Israël: "High-level replication of human immunodeficiency virus in thymocytes requires NF-kappaB activation through interaction with thymic epithelial cells." in: Journal of virology, Vol. 73, Issue 3, pp. 2064-73, (1999) (PubMed).

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL-1beta

Background: IL-1b, IL-1beta

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome