PSMA1 antibody

Catalog No. ABIN1385865

Product Details anti-PSMA1 Antibody

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S C2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PSMA1

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Abstract: PSMA1 Products

Synonyms: PSMA1 antibody, pros30 antibody, DDBDRAFT_0204226 antibody, DDBDRAFT_0214956 antibody, DDB_0204226 antibody, DDB_0214956 antibody, C2 antibody, HC2 antibody, Pros-30 antibody, alpha-type antibody, NU antibody, PROS30 antibody, CC2 antibody, zgc:92726 antibody, 143314_at antibody, Alpha-6 antibody, CG4904 antibody, Dmel\CG4904 antibody, PROS-35 antibody, PROS-Dm35 antibody, Pros-35 antibody, Pros-Dm35 antibody, Prosalpha6 antibody, alpha6 antibody, alpha_dm antibody, anon-SAGE:Wang-116 antibody, pros 35 antibody, pros35 antibody, proteasome subunit alpha 1 antibody, proteasome subunit alpha type 1 antibody, 20S proteasome subunit C2 antibody, proteasome (prosome, macropain) subunit, alpha type 1 antibody, proteasome subunit alpha 1 L homeolog antibody, Proteasome alpha6 subunit antibody, PSMA1 antibody, psma1 antibody, CNB05540 antibody, psmA1 antibody, Psma1 antibody, psma1.L antibody, Prosalpha6 antibody

Background:

Synonyms: 20S Proteasome 1, 30 kDa prosomal protein, HC 2, HC2, Macropain subunit C2, Macropain subunit nu, Multicatalytic endopeptidase complex subunit C2, NU antibody PROS 30, PROS-30, PROS30, Proteasome prosome macropain subunit alpha type 1, Proteasome alpha 1 subunit, Proteasome component C2, Proteasome nu chain, Proteasome subunit alpha type 1, Proteasome subunit alpha type I, Proteasome subunit alpha type-1, Proteasome subunit nu, Protein P30 33K, PSA1_HUMAN, PSC 2, PSC2, PSMA 1, psmA1.

Background: Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.

Gene ID: 5682

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA