GABRg1 antibody (AA 65-160)
-
- Target See all GABRg1 Antibodies
- GABRg1 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 1 (GABRg1))
-
Binding Specificity
- AA 65-160
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GABRg1 antibody is un-conjugated
- Application
- ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GABRG1/GABA A Receptor gamma 1
- Isotype
- IgG
- Top Product
- Discover our top product GABRg1 Primary Antibody
-
-
- Application Notes
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- GABRg1 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 1 (GABRg1))
- Alternative Name
- GABRG1/GABA A Receptor gamma 1 (GABRg1 Products)
- Synonyms
- GabaA antibody, GabaA/BZ antibody, gamma-aminobutyric acid type A receptor gamma1 subunit antibody, gamma-aminobutyric acid type A receptor gamma 1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 antibody, GABRG1 antibody, Gabrg1 antibody
- Background
-
Synonyms: GABAA receptor subunit gamma 1, GabaA/BZ, GABRG 1, GABRG1, Gamma aminobutyric acid GABA A receptor subunit gamma 1, Gamma aminobutyric acid A receptor, gamma 1, GBRG1,
Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system, GABA functions as the main inhibitory transmitter by increasing a Cl- (chloride) conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as a third class of receptors called GABAC. The Gamma subunit of GABAA receptors are important for benzodiazepine binding and modulation of GABA-mediated Cl- current. GABAA R Gamma 1 (gamma-aminobutyric acid (GABA) A receptor, gamma 1), also known as GABRG1, is a 465 amino acid multi-pass membrane protein belonging to the ligand-gated ionic channel (TC 1.A.9) family. GABAA R gamma 1 participates in neurotransmission inhibition and has been linked to alcohol dependence.
- Gene ID
- 2565
- UniProt
- Q8N1C3
- Pathways
- Synaptic Membrane
-