DUOXA1 antibody (AA 101-200)

Catalog No. ABIN1387935

This anti-DUOXA1 antibody is a Rabbit Polyclonal antibody detecting DUOXA1 in ELISA, WB, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). Suitable for Human.

Quick Overview for DUOXA1 antibody (AA 101-200) (ABIN1387935)

Target: DUOXA1 (Dual Oxidase Maturation Factor 1 (DUOXA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOXA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DUOXA1 Antibody

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUOXA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DUOXA1

Target: DUOXA1 (Dual Oxidase Maturation Factor 1 (DUOXA1))

Alternative Name: DUOXA1

Background:

Synonyms: DOXA1_HUMAN, Dual oxidase activator 1, Dual oxidase maturation factor 1, duoxa1, NIP, Numb interacting protein, Numb-interacting protein, NUMBIP.

Background: DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Gene ID: 90527