EGFLAM antibody (AA 111-210) (Biotin)
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- Target See all EGFLAM Antibodies
- EGFLAM (EGF-Like, Fibronectin Type III and Laminin G Domains (EGFLAM))
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Binding Specificity
- AA 111-210
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EGFLAM antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Pikachurin
- Isotype
- IgG
- Top Product
- Discover our top product EGFLAM Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- EGFLAM (EGF-Like, Fibronectin Type III and Laminin G Domains (EGFLAM))
- Alternative Name
- EGFLAM/Pikachurin (EGFLAM Products)
- Synonyms
- AGRINL antibody, AGRNL antibody, 5930412K08 antibody, AU040377 antibody, RGD1306592 antibody, EGF like, fibronectin type III and laminin G domains antibody, EGF-like, fibronectin type III and laminin G domains antibody, EGFLAM antibody, Egflam antibody
- Background
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Synonyms: fibronectin type-III and laminin G-like domain-containing protein, Agrin-like protein, AGRINL, AGRNL, EGF-like, EGF-like, fibronectin type III and laminin G domains, EGF-like, fibronectin type-III and laminin G-like domain-containing protein, EGFLA_HUMAN, EGFLAM, FLJ39155, Pikachurin.
Background: EGFLAM is a 1,017 amino acid secreted protein containing three EGF-like domains, two fibronectin type-III domains, and three laminin G-like domains. Colocalizing with bassoon, CtBP and dystroglycan in photoreceptor synaptic terminals, EGFLAM is involved in retinal photoreceptor ribbon synapse formation. EGFLAM may also promote matrix assembly and cell adhesion. Existing as five alternatively spliced isoforms, the gene encoding EGFLAM maps to human chromosome 5p13.2. Chromosome 5 makes up approximately 6 % of the human genome and contains 181 million base pairs, which encode 1,000 genes. Cockayne syndrome, Treacher Collins syndrome, acute myelogenous leukemias and myelodysplastic syndrome are associated with genes present on chromosome 5.
- Pathways
- Glycosaminoglycan Metabolic Process
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