NMNAT1 antibody (Alexa Fluor 488)

Catalog No. ABIN1393030

Product Details anti-NMNAT1 Antibody (Alexa Fluor 488)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMNAT1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nmnat1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Alternative Name: Nmnat1 (NMNAT1 Products)

Synonyms: id:ibd5068 antibody, im:7144541 antibody, zgc:110243 antibody, LCA9 antibody, NMNAT antibody, PNAT1 antibody, 2610529L11Rik antibody, 5730441G13Rik antibody, D4Cole1e antibody, nmnat antibody, nicotinamide mononucleotide adenylyltransferase 1 antibody, nicotinamide nucleotide adenylyltransferase 1 antibody, CpipJ_CPIJ015320 antibody, PTRG_06486 antibody, nmnat1 antibody, NMNAT1 antibody, Nmnat1 antibody

Background:

Synonyms: NaMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1, nicotinamide nucleotide adenylyltransferase 1, nicotinate nucleotide adenylyltransferase 1, Nicotinate-nucleotide adenylyltransferase 1, NMN adenylyltransferase 1, NMNA1_HUMAN, Nmnat 1, Nmnat1, Nmnat-1, OTTHUMP00000001731, OTTHUMP00000001732, OTTHUMP00000035892, PNAT 1, PNAT1, pyridine nucleotide adenylyltransferase 1.

Background: Nicotinamide adenine dinucleotide (NMNAT) is an essential cofactor involved in fundamental processes in cell metabolism. NMNAT plays a key role in NAD(+) biosynthesis, catalysing the condensation of nicotinamide mononucleotide and ATP, and yielding NAD(+) and pyrophosphate. NMNAT appears to be a substrate of nuclear kinases and contains at least three potential phosphorylation sites. The interaction of NMNAT with nuclear proteins is likely to be modulated by phosphorylation. NMNAT is widely expressed with highest levels in skeletal muscle, heart, liver and kidney.