P2RX7 antibody (AA 115-160) (Alexa Fluor 350)
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- Target See all P2RX7 Antibodies
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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Binding Specificity
- AA 115-160
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This P2RX7 antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human P2RX7
- Isotype
- IgG
- Top Product
- Discover our top product P2RX7 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Alternative Name
- P2RX7 (P2RX7 Products)
- Synonyms
- p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
- Background
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Synonyms: P2X7, P2X purinoceptor 7, ATP receptor, P2Z receptor, Purinergic receptor, P2RX7
Background: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
- Gene ID
- 5027
- UniProt
- Q99572
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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