alpha Fetoprotein antibody (AA 521-609) (Alexa Fluor 350)
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- Target See all alpha Fetoprotein (AFP) Antibodies
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Binding Specificity
- AA 521-609
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This alpha Fetoprotein antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Monkey
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human AFP
- Isotype
- IgG
- Top Product
- Discover our top product AFP Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Alternative Name
- AFP (AFP Products)
- Synonyms
- FETA antibody, HPAFP antibody, alpha fetoprotein antibody, alpha-fetoprotein antibody, AFP antibody, Afp antibody
- Background
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Synonyms: Alpha Fetoprotein, Alpha-fetoprotein, AFP, alpha 1 fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha fetoglobulin, alpha Fetoprotein, Alpha fetoprotein precursor, FETA, HPAFP, FETA_HUMAN.
Background: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
- Gene ID
- 174
- UniProt
- P02771
- Pathways
- C21-Steroid Hormone Metabolic Process
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