CUEDC1 antibody (AA 251-350) (Alexa Fluor 350)

Catalog No. ABIN1398021

Product Details anti-CUEDC1 Antibody (Alexa Fluor 350)

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC1 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CUEDC1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CUEDC1

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Alternative Name: CUEDC1 (CUEDC1 Products)

Synonyms: AI841487 antibody, C330016O16Rik antibody, RGD1304861 antibody, CUEDC1 antibody, zgc:153423 antibody, zgc:162271 antibody, CUE domain containing 1 antibody, CUE domain containing 1 L homeolog antibody, CUE domain containing 1a antibody, CUE domain containing 1b antibody, CUEDC1 antibody, Cuedc1 antibody, cuedc1.L antibody, cuedc1 antibody, cuedc1a antibody, cuedc1b antibody

Background:

Synonyms: CUE domain containing protein 1, CUED1_HUMAN.

Background: The coupling of ubiquitin conjugation to endoplasmic reticulum (ER) degradation (CUE) domain functions as a ubiquitin (UB) binding domain that is approximately 40 amino acids in length. Present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways, CUE domains can bind monoubiquitin and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. Two isoforms of CUEDC1 exist due to alternative splicing events.

Gene ID: 404093