CaM I (pSer102) antibody (Biotin)
-
- Target
- CaM I
- Binding Specificity
- pSer102
- Reactivity
- Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Biotin
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated syntheticphosphopeptide derived from human CaM I around the phosphorylation site of Ser 102
- Isotype
- IgG
-
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- CaM I
- Background
-
Synonyms: p-CaM I Ser 102, CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, Calmodulin 1, Calmodulin1, CAM 1, CAM 2, CAM 3, CaM, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit, Calmodulin1, Calmodulin 1, Calmodulin-1, Calmodulin2, Calmodulin 2, Calmodulin-2, Calmodulin3, Calmodulin 3, Calmodulin-3.
Background: Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100 % in various studies, as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30 % of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.
- Gene ID
- 801
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