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IPO7 antibody (AA 365-460) (AbBy Fluor® 647)

IPO7 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN1399908
  • Target See all IPO7 Antibodies
    IPO7 (Importin 7 (IPO7))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-460
    Reactivity
    • 49
    • 21
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IPO7 antibody is conjugated to AbBy Fluor® 647
    Application
    • 41
    • 19
    • 19
    • 12
    • 12
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RanBP7/Importin 7
    Isotype
    IgG
    Top Product
    Discover our top product IPO7 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IPO7 (Importin 7 (IPO7))
    Alternative Name
    RanBP7 (IPO7 Products)
    Synonyms
    fb33d09 antibody, wu:fb33d09 antibody, zgc:66425 antibody, zgc:76878 antibody, imp7 antibody, ranbp7 antibody, Imp7 antibody, RANBP7 antibody, A330055O14Rik antibody, C330016G14 antibody, Ranbp7 antibody, importin 7 antibody, importin 7 S homeolog antibody, importin-7 antibody, karyopherin antibody, ipo7 antibody, ipo7.S antibody, IPO7 antibody, CpipJ_CPIJ002096 antibody, PTRG_08544 antibody, SJAG_03693 antibody, NAEGRDRAFT_71372 antibody, VDBG_01971 antibody, MGYG_08162 antibody, Tsp_01943 antibody, Tsp_01946 antibody, Ipo7 antibody
    Background

    Synonyms: Imp 7, Imp7, Importin-7, Importin7, IPO 7, IPO7, IPO7_HUMAN, Ran binding protein 7, Ran-binding protein 7, RANBP 7, RanBP7.

    Background: Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.

    Pathways
    Protein targeting to Nucleus
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