HNRNPU antibody (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A)) AA 1-40 (Alexa Fluor 647)

Catalog No. ABIN1400790

Product Details anti-HNRNPU Antibody

Target: HNRNPU

Binding Specificity: AA 1-40

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPU antibody is conjugated to Alexa Fluor 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human hnRNP U

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Expiry Date: 12 months

Target Details for HNRNPU

Target: HNRNPU

Alternative Name: HnRNP U (HNRNPU Products)

Synonyms: AA408410, AI256620, AL024194, AL024437, AW557595, C86794, Hnrpu, SAFA, Sp120, hnRNP U, SN1, HNRPU, SAF-A, U21.1, saf-a, heterogeneous nuclear ribonucleoprotein U, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A), Hnrnpu, HNRNPU, hnrnpu.S

Background:

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are thought to be involved in pre-mRNA processing. However, its role in the regulation of gene expression is as yet poorly understood. Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. Recently, hnRNP proteins have been shown to hinder communication between factors bound to different splice sites. Conversely, several reports have described a positive role for some hnRNP proteins in pre-mRNA splicing. hnRNP-U, also termed scaffold attachment factor A (SAF-A), binds to pre-mRNA and nuclear matrix/scaffold attachment region DNA elements.

Synonyms: Heterogeneous nuclear ribonucleoprotein U, hnRNP U, hnRNP U protein, HNRNPU, hnRNPU protein, HNRPU, HNRPU_HUMAN, p120, p120 nuclear protein, pp120, SAF A, SAF-A, SAFA, Scaffold attachment factor A, U21.1, GRIP120, C1orf199

Gene ID:

UniProt: Q00839