CHRM4 antibody (AA 1-31) (HRP)

Catalog No. ABIN1412456

Product Details anti-CHRM4 Antibody (HRP)

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Binding Specificity: AA 1-31

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM4 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHRM4/mAChR M4

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CHRM4

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Alternative Name: CHRM4/mAChR M4 (CHRM4 Products)

Synonyms: M3R antibody, M4 antibody, HM4 antibody, M4R antibody, Chrm-4 antibody, cholinergic receptor muscarinic 4 antibody, cholinergic receptor, muscarinic 4 antibody, CHRM4 antibody, chrm4 antibody, Chrm4 antibody

Background:

Synonyms: HM4, M4R, Muscarinic acetylcholine receptor M4, CHRM4

Background: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

Gene ID: 1132

UniProt: P08173

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane