GABRB2 antibody (AA 251-350) (Cy3)

Catalog No. ABIN1412841

The Cy3-conjugated Rabbit Polyclonal anti-GABRB2 antibody (ABIN1412841) specifically detects GABRB2 in WB, IF (cc) and IF (p). The antibody is reactive with Rat and Mouse samples.

Quick Overview for GABRB2 antibody (AA 251-350) (Cy3) (ABIN1412841)

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GABRB2 Antibody (Cy3)

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRB2/GABA A Receptor beta 2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABRB2/GABA A Receptor beta 2

Background:

Synonyms: GABA, GABAA receptor subunit beta-2, GABRB2, Gamma aminobutyric acid GABA A receptor, beta 2, Gamma aminobutyric acid A receptor beta 2, Gamma-aminobutyric acid receptor subunit beta-2, Gamma-aminobutyric-acid receptor subunit beta-2, GBRB2_HUMAN,

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.

Pathways: Sensory Perception of Sound, Synaptic Membrane