GABRB2 antibody (AA 343-430)

Catalog No. ABIN1742467

This Rabbit Polyclonal antibody specifically detects GABRB2 in WB, IHC, IHC (fro) and ICC. It exhibits reactivity toward Rat and Mouse.It has been mentioned in 1 publication

Quick Overview for GABRB2 antibody (AA 343-430) (ABIN1742467)

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-GABRB2 Antibody

Binding Specificity: AA 343-430

Purpose: Rabbit anti-GABA-A receptor beta2 antibody

Specificity: Specific for GABA-A receptor beta2.

Cross-Reactivity (Details): Reacts with: rat (P63138), mouse (P63137). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 343 to 430 from rat GABA-A receptor beta2 (UniProt Id: P63138)

Application Details

Application Notes: WB:1 : 1000 , IHC-P:not tested yet IHC-Fr:1 : 500, IHC-G:1 : 500,

Comment:

WB: This protein aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples. IHC: This antibody requires antigen retrieval with pepsin according to: Lorincz A & Nusser Z (2008).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-GABRB2 antibody (ABIN1742467)

Kerti-Szigeti, Nusser: "Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells." in: eLife, Vol. 5, (2016) (PubMed).

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABA-A receptor beta2

Background:

Synonyms: GABA receptor, Gabrb2

Antigen Information: GABA-A receptors are involved in inhibitory neurotransmission

UniProt: P63138

Pathways: Sensory Perception of Sound, Synaptic Membrane