HNRNPC antibody (AA 21-120) (HRP)

Catalog No. ABIN1415289

Product Details anti-HNRNPC Antibody (HRP)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Binding Specificity: AA 21-120

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HNRPC

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRPC (HNRNPC Products)

Synonyms: C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, SNRPC antibody, MGC53243 antibody, HNRNPC antibody, bZ1G18.4 antibody, fb57h12 antibody, fi16b11 antibody, wu:fb57h12 antibody, wu:fi16b11 antibody, zgc:55701 antibody, AL022939 antibody, D14Wsu171e antibody, Hnrpc antibody, Hnrpc1 antibody, Hnrpc2 antibody, hnRNPC1 antibody, hnRNPC2 antibody, hnrnp-C antibody, hnRNP C antibody, hnrnp antibody, hnrpc antibody, snrpc antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antibody, heterogeneous nuclear ribonucleoprotein C antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antibody, HNRNPC antibody, hnrnpc.S antibody, hnrnpc antibody, Hnrnpc antibody, hnrnpc.L antibody

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein C, Heterogeneous nuclear ribonucleoproteins C1/C2, HNRNP, hnRNP C1 / hnRNP C2, hnRNP C1/C2, hnRNPC, HNRPC, HNRPC_HUMAN, Nuclear ribonucleoprotein particle C1 protein, Nuclear ribonucleoprotein particle C2 protein, SNRPC.

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Gene ID: 3183