RNF6 antibody (HRP)

Catalog No. ABIN1419124

Product Details anti-RNF6 Antibody (HRP)

Target: RNF6 (RING Finger Protein 6 (RNF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF6 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Alternative Name: RNF6 (RNF6 Products)

Synonyms: 1200013I08Rik antibody, 5730419H05Rik antibody, AA537053 antibody, ring finger protein 6 antibody, ring finger protein (C3H2C3 type) 6 antibody, RNF6 antibody, Rnf6 antibody

Background:

Synonyms: E3 ubiquitin-protein ligase RNF6, Ring finger protein C3H2C3 type 6, Ring finger protein 6, RING H2 protein, RING H2 protein RNF6, RNF 6, RNF6, RNF6_HUMAN, SPG2.

Background: The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008].

Gene ID: 6049

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size