UBE2V2 antibody (HRP)

Catalog No. ABIN1420240

Product Details anti-UBE2V2 Antibody (HRP)

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2V2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMS2/EDPF1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UBE2V2

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Alternative Name: EDPF1 (UBE2V2 Products)

Synonyms: DDVIT1 antibody, DDVit-1 antibody, EDAF-1 antibody, EDPF-1 antibody, EDPF1 antibody, MMS2 antibody, UEV-2 antibody, UEV2 antibody, mms2 antibody, uev2 antibody, edpf1 antibody, uev-2 antibody, ddvit1 antibody, edaf-1 antibody, edpf-1 antibody, ddvit-1 antibody, 1110021H13Rik antibody, 4632410D19Rik antibody, 5730524P06Rik antibody, 6820402M05 antibody, AI848315 antibody, C81524 antibody, wu:fb18b11 antibody, wu:fb24d11 antibody, zgc:63717 antibody, UBE2V2 antibody, TMEM189-UBE2V1 antibody, ubiquitin conjugating enzyme E2 V2 antibody, ubiquitin-conjugating enzyme E2 variant 2 antibody, ubiquitin conjugating enzyme E2 V2 S homeolog antibody, Ubiquitin-conjugating enzyme E2 variant 2 antibody, UBE2V2 antibody, Ube2v2 antibody, ube2v2 antibody, ube2v2.S antibody, PTRG_00824 antibody, ub2v2 antibody, Tsp_08004 antibody

Background:

Synonyms: 1 alpha 25 dihydroxyvitamin D3 inducible, DDVit 1, DDVIT1, EDAF-1, EDAF1, EDPF-1, EDPF1, Enterocyte dferentiation associated factor EDAF 1, Enterocyte dferentiation promoting factor, Enterocyte dferentiation-associated factor 1, Enterocyte dferentiation-promoting factor 1, Methyl methanesulfonate sensitive 2, MMS 2, MMS2, MMS2 homolog, UB2V2_HUMAN, UBE2V 2, UBE2V2, Ubiquitin conjugating enzyme E2 variant 2, Ubiquitin conjugating enzyme E2v2, Ubiquitin-conjugating enzyme E2 variant 2, UEV 2, UEV2, Vitamin D3 inducible protein, Vitamin D3-inducible protein.

Background: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Gene ID: 7336

Pathways: Positive Regulation of Response to DNA Damage Stimulus