CREG2 antibody (HRP)

Catalog No. ABIN1423540

Product Details anti-CREG2 Antibody (HRP)

Target: CREG2 (Cellular Repressor of E1A-Stimulated Genes 2 (CREG2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREG2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CREG2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CREG2

Target: CREG2 (Cellular Repressor of E1A-Stimulated Genes 2 (CREG2))

Alternative Name: CREG2 (CREG2 Products)

Synonyms: zgc:92257 antibody, A830098L22Rik antibody, Creg2-ps1 antibody, RGD1564056 antibody, cellular repressor of E1A-stimulated genes 2 antibody, cellular repressor of E1A stimulated genes 2 antibody, creg2 antibody, CREG2 antibody, Creg2 antibody

Background:

Synonyms: CREG 2, CREG-2, Cellular repressor of E1A stimulated genes 2, CREG2_HUMAN.

Background: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG (cellular repressor of E1A-stimulated genes) is a cellular protein that antagonizes transcriptional activation and cellular transformation by E1A. CREG was initially isolated in a yeast two-hybrid screen due to its interaction with the TATA-binding protein, TBP. A member of the CREG family, CREG2 (cellular repressor of E1A-stimulated genes 2) is a novel protein that shares 35 % homology with CREG and is expressed at highest levels in brain. CREG2 is a secreted protein containing 290 amino acids whose N-terminus is thought to function as a signal sequence. The gene encoding CREG2 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

Gene ID: 200407