×
For best experience we recommend to activate Javascript in your browser.
CDKN1C antibody (N-Term)
CDKN1C
Reactivity: Human
WB, IF, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDKN1C Antibody
(hide)
Target
See all CDKN1C Antibodies
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Binding Specificity
All epitopes for CDKN1C antibodies
N-Term
Reactivity
All reactivities for CDKN1C antibodies
Human
Host
All hosts for CDKN1C antibodies
Rabbit
Clonality
All clonalities for CDKN1C antibodies
Polyclonal
Conjugate
All conjugates for CDKN1C antibodies
This CDKN1C antibody is un-conjugated
Application
All applications for CDKN1C antibodies
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
Purification
Affinity chromatography purified via peptide column
Immunogen
A 17 amino acid synthetic peptide near the amino terminus of Human CDKN1C
Isotype
IgG
Top Product
Discover our top product CDKN1C Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CDKN1C
(hide)
Target
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Alternative Name
CDKN1C / KIP2 (CDKN1C Products )
Synonyms
BWCR antibody, BWS antibody, KIP2 antibody, WBS antibody, p57 antibody, p57Kip2 antibody, cb961 antibody, p27Xic1-a antibody, zgc:86618 antibody, AL024410 antibody, CDKI antibody, Kip2 antibody, p57(kip2) antibody, p57KIP2 antibody, cyclin dependent kinase inhibitor 1C antibody, cyclin-dependent kinase inhibitor 1Ca antibody, cyclin-dependent kinase inhibitor 1C (P57) antibody, cyclin-dependent kinase inhibitor 1C antibody, CDKN1C antibody, cdkn1ca antibody, Cdkn1c antibody
Background
The cyclin-dependent kinase inhibitor 1C (CDKN1C), also known as p57KIP2, is a tight-binding, strong inhibitor of several G1 cyclin/CDK complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndrome, a cancer-predisposing syndrome, suggesting that this gene is a tumor suppressor candidate. CDKN1C is widely expressed during organogenesis with its expression declining after maturity. It is part of the CIP/KIP family of cyclin-dependent inhibitors (CKIs) which also includes CDKN1A and CDKN1B.Synonyms: Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57KIP2
Molecular Weight
35 kDa
Gene ID
1028
NCBI Accession
NP_000067
Pathways
Cell Division Cycle , Dopaminergic Neurogenesis
Recently viewed
(hide)