RUSC2 antibody (N-Term)

Catalog No. ABIN1450112

The Rabbit Polyclonal anti-RUSC2 antibody is suitable to detect RUSC2 in samples from Human and Mouse. It has been validated for WB, IHC (p), IF and EIA.

Quick Overview for RUSC2 antibody (N-Term) (ABIN1450112)

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUSC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-RUSC2 Antibody

Binding Specificity: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide from near the amino terminus of Human RUSC2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RUSC2

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Alternative Name: RUSC2

Background: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.Synonyms: Iporin, RUN and SH3 domain containing protein 2

Gene ID: 9853

NCBI Accession: NP_001098673