PERK antibody (AA 947-996)

Catalog No. ABIN1450662

The Rabbit Polyclonal anti-PERK antibody (ABIN1450662) specifically detects PERK in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PERK antibody (AA 947-996) (ABIN1450662)

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PERK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PERK Antibody

Binding Specificity: AA 947-996

Specificity:

PEK/PERK Antibody detects endogenous levels of total PEK/PERK protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human EIF2AK3.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for PERK

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Alternative Name: PEK/PERK

Background:

Synonyms: E2AK3, EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3 precursor, HsPEK, PEK, PERK, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, kinase PERK

NCBI Gene Symbol: EIF2AK3

Molecular Weight: 125 kDa

Gene ID: 9451

OMIM: 226980

UniProt: Q9NZJ5

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response