GLRB antibody (AA 211-260)

Catalog No. ABIN1451271

The Rabbit Polyclonal anti-GLRB antibody (ABIN1451271) specifically detects GLRB in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLRB antibody (AA 211-260) (ABIN1451271)

Target: GLRB (Glycine Receptor, beta (GLRB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GLRB Antibody

Binding Specificity: AA 211-260

Purpose: GlyRβ Antibody

Specificity: GlyRβ Polyclonal Antibody detects endogenous levels of GlyRβ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Alternative Name: GLRB

Background:

Synonyms: GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunit

Background: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Gene Name: GLRB

Protein Name: Glycine receptor subunit beta

Molecular Weight: 56 kDa

Gene ID: 2743

OMIM: 138492

UniProt: P48167