IQGAP1 antibody (AA 247-296)

Catalog No. ABIN1451508

The Rabbit Polyclonal anti-IQGAP1 antibody (ABIN1451508) specifically detects IQGAP1 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for IQGAP1 antibody (AA 247-296) (ABIN1451508)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IQGAP1 Antibody

Binding Specificity: AA 247-296

Purpose: IQGAP1 Antibody

Specificity: IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background:

Synonyms: IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195

Background: IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

Gene Name: IQGAP1

Protein Name: Ras GTPase-activating-like protein IQGAP1

Molecular Weight: 189 kDa

Gene ID: 8826

OMIM: 603379

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2