IL-21 antibody (AA 91-140)

Catalog No. ABIN1452162

The Rabbit Polyclonal anti-IL-21 antibody (ABIN1452162) specifically detects IL-21 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL-21 antibody (AA 91-140) (ABIN1452162)

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-21 Antibody

Binding Specificity: AA 91-140

Purpose: IL-21 Antibody

Specificity: IL-21 Polyclonal Antibody detects endogenous levels of IL-21 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL21. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IL-21

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Alternative Name: IL21

Background:

Synonyms: IL21, Interleukin-21, IL-21, Za11

Background: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Gene Name: IL21

Protein Name: Interleukin-21

Molecular Weight: 17 kDa

Gene ID: 59067

OMIM: 605384

UniProt: Q9HBE4

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response