PIK3CA antibody (AA 470-519)

Catalog No. ABIN1453773

This anti-PIK3CA antibody is a Rabbit Polyclonal antibody detecting PIK3CA in WB, IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for PIK3CA antibody (AA 470-519) (ABIN1453773)

Target: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3CA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PIK3CA Antibody

Binding Specificity: AA 470-519

Specificity:

PI 3-kinase p110alpha antibody detects endogenous levels of PI 3-kinase p110alpha.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for PIK3CA

Target: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Alternative Name: PI 3-kinase p110Alpha

Background:

Synonyms: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, phosphoinositide-3-kinase catalytic alpha polypeptide, PI3-kinase p110 alpha, PI3K, PI3K p110-alpha, PK3CA, PtdIns-3-kinase p110

NCBI Gene Symbol: PIK3CA

Molecular Weight: 124 kDa

Gene ID: 5290

OMIM: 171834

UniProt: P42336

Pathways: PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling