Caspase 8 antibody (Internal Region) (Sepharose)

Catalog No. ABIN1490387

The Rabbit Polyclonal anti-Caspase 8 antibody has been validated for IP. It is suitable to detect Caspase 8 in samples from Human, Mouse and Rat.

Quick Overview for Caspase 8 antibody (Internal Region) (Sepharose) (ABIN1490387)

Target: Caspase 8 (CASP8)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is conjugated to Sepharose

Application: Immunoprecipitation (IP)

Product Details anti-Caspase 8 Antibody (Sepharose)

Binding Specificity: Internal Region

Specificity: Human, rat, mouse. No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the middle region of human Caspase-8(P18), different to the related mouse sequence by a single amino acids.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 % slurry in PBS,  pH 7.2, 0.01 mg sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades