FAK antibody (pSer910)

Catalog No. ABIN1531596

This anti-FAK antibody is a Rabbit Polyclonal antibody detecting FAK in ELISA, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for FAK antibody (pSer910) (ABIN1531596)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAK antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FAK Antibody

Binding Specificity: AA 876-925, pSer910

Specificity:

FAK (Phospho-Ser910) Antibody detects endogenous levels of FAK only when phosphorylated at Ser910.

PhosphorylationH:S910 M:S948 R:S913

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FAK around the phosphorylation site of Ser910.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.395482 (NCBI Gene Symbol: PTK2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name: FAK

Background:

Synonyms: FADK 1, FAK1, Focal adhesion kinase 1, pp125FAK, Protein- tyrosine kinase 2, PTK2

NCBI Gene Symbol: PTK2

Molecular Weight: 119 kDa

Gene ID: 5747

OMIM: 600758

UniProt: Q05397

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling