Nonvoltage-Gated Sodium Channel 1 (AA 581-630), (pThr615) antibody

Catalog No. ABIN1531692

Product Details

Target: Nonvoltage-Gated Sodium Channel 1

Binding Specificity: AA 581-630, pThr615

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Specificity:

Nonvoltage-gated Sodium Channel 1 (Phospho-Thr615) Antibody detects endogenous levels of Nonvoltage-gated Sodium Channel 1 only when phosphorylated at Thr615.

PhosphorylationH:T615 M:T613 R:T613

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Nonvoltage-gated Sodium Channel 1 around the phosphorylation site of Thr615.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.414614 (NCBI Gene Symbol: SCNN1B)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details

Target: Nonvoltage-Gated Sodium Channel 1

Background:

Synonyms: Amiloride-sensitive sodium channel beta-subunit, Beta ENaC, Beta NaCH, ENaCB, Epithelial Na channel beta subunit, Nonvoltage-gated sodium channel 1 beta subunit, SCAB, SCNEB, SCNN1B, SCNNB

NCBI Gene Symbol: SCNN1B

Molecular Weight: 72 kDa

Gene ID: 6338

OMIM: 177200

UniProt: P51168