JAK1 antibody (pTyr1022)

Catalog No. ABIN1531881

This anti-JAK1 antibody is a Rabbit Polyclonal antibody detecting JAK1 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for JAK1 antibody (pTyr1022) (ABIN1531881)

Target: JAK1 (Janus Kinase 1 (JAK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-JAK1 Antibody

Binding Specificity: AA 988-1037, pTyr1022

Specificity:

JAK1 (Phospho-Tyr1022) Antibody detects endogenous levels of JAK1 only when phosphorylated at Tyr1022.

PhosphorylationH:Y1022 M:Y1033 R:Y1078

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.207538 (NCBI Gene Symbol: JAK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for JAK1

Target: JAK1 (Janus Kinase 1 (JAK1))

Alternative Name: JAK1

Background:

Synonyms: JAK-1, JAK1, JAK1A, Janus kinase 1, kinase Jak1

NCBI Gene Symbol: JAK1

Molecular Weight: 131 kDa

Gene ID: 3716

OMIM: 147795

UniProt: P23458

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response