MAP3K1 antibody (pThr1402)

Catalog No. ABIN1532054

This anti-MAP3K1 antibody is a Rabbit Polyclonal antibody detecting MAP3K1 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for MAP3K1 antibody (pThr1402) (ABIN1532054)

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MAP3K1 Antibody

Binding Specificity: AA 1368-1417, pThr1402

Specificity:

MAP3K1 (Phospho-Thr1402) Antibody detects endogenous levels of MAP3K1 only when phosphorylated at Thr1402.

PhosphorylationH:T1402 M:T1381 R:T1381

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP3K1 around the phosphorylation site of Thr1402.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.657756 (NCBI Gene Symbol: MAP3K1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MAP3K1

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Alternative Name: MAP3K1

Background:

Synonyms: MAPK/ERK kinase kinase 1, MEK kinase 1, MEKK 1

NCBI Gene Symbol: MAP3K1

Molecular Weight: 161 kDa

Gene ID: 4214

OMIM: 600982

UniProt: Q13233

Pathways: MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades