PLK1 antibody (AA 176-225)
Quick Overview for PLK1 antibody (AA 176-225) (ABIN1532395)
Target
See all PLK1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 176-225
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Purpose
- Plk Antibody
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Specificity
- Plk Polyclonal Antibody detects endogenous levels of Plk protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human PLK1. AA range:176-225
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Alternative Name
- PLK1
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Background
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Synonyms: PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],
Gene Name: PLK1
Protein Name: Serine/threonine-protein kinase PLK1
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Molecular Weight
- 68 kDa
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Gene ID
- 5347
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OMIM
- 602098
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UniProt
- P53350
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Pathways
- Cell Division Cycle, M Phase
Target
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