Tuberin antibody (AA 905-954)
Quick Overview for Tuberin antibody (AA 905-954) (ABIN1532423)
Target
See all Tuberin (TSC2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 905-954
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Purpose
- Tuberin Antibody
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Specificity
- Tuberin Polyclonal Antibody detects endogenous levels of Tuberin protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2. AA range:905-954
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Isotype
- IgG
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 23GB1120 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 23GB1000 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reactivity: Human IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reactivity: Human DB, IF Host: Rabbit Polyclonal RB11388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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Alternative Name
- Tuberin/TSC2
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Background
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Synonyms: TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Gene Name: TSC2
Protein Name: Tuberin
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Molecular Weight
- 200 kDa
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Gene ID
- 7249
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OMIM
- 191092
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UniProt
- P49815
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Pathways
- RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Target
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