RASGRF1 antibody (AA 882-931)

Catalog No. ABIN1532485

The Rabbit Polyclonal anti-RASGRF1 antibody is suitable to detect RASGRF1 in samples from Mouse and Rat. It has been validated for IHC, WB, ELISA and IF.

Quick Overview for RASGRF1 antibody (AA 882-931) (ABIN1532485)

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-RASGRF1 Antibody

Binding Specificity: AA 882-931

Purpose: Ras-GRF1 Antibody

Specificity: Ras-GRF1 Polyclonal Antibody detects endogenous levels of Ras-GRF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Ras-GRF1. AA range:882-931

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Alternative Name: Ras-GRF1

Background:

Synonyms: RASGRF1, CDC25, GNRP, GRF1, Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25

Background: RASGRF1 (Ras Protein Specific Guanine Nucleotide Releasing Factor 1) is a Protein Coding gene. Diseases associated with RASGRF1 include bleeding disorder, platelet-type, 18 and refractive error. Among its related pathways are Signaling by GPCR and Immune System. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS. romotes the exchange of Ras-bound GDP by GTP.

Gene Name: RASGRF1

Protein Name: Ras-specific guanine nucleotide-releasing factor 1

Molecular Weight: 145 kDa

OMIM: 606600

UniProt: Q13972

Pathways: RTK Signaling, Cell Division Cycle, M Phase