JAK3 antibody (AA 751-800)

Catalog No. ABIN1532701

The Rabbit Polyclonal anti-JAK3 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect JAK3 in samples from Human, Mouse and Rat.

Quick Overview for JAK3 antibody (AA 751-800) (ABIN1532701)

Target: JAK3 (Janus Kinase 3 (JAK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-JAK3 Antibody

Binding Specificity: AA 751-800

Specificity:

JAK3 Antibody detects endogenous levels of total JAK3 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human JAK3.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.515247 (NCBI Gene Symbol: JAK3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for JAK3

Target: JAK3 (Janus Kinase 3 (JAK3))

Alternative Name: JAK3

Background:

Synonyms: JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3

NCBI Gene Symbol: JAK3

Molecular Weight: 125 kDa

Gene ID: 3718

OMIM: 600173

UniProt: P52333

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response