NGFR antibody (AA 121-170)

Catalog No. ABIN1533595

The Rabbit Polyclonal anti-NGFR antibody is suitable to detect NGFR in samples from Human, Rat and Mouse. It has been validated for WB, IF and ELISA.

Quick Overview for NGFR antibody (AA 121-170) (ABIN1533595)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-NGFR Antibody

Binding Specificity: AA 121-170

Purpose: NGFR p75 Antibody

Specificity: NGFR p75 Polyclonal Antibody detects endogenous levels of NGFR p75 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TNR16. AA range:121-170

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Background:

Synonyms: NGFR, TNFRSF16, Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD antigen CD271

Background: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008],

Gene Name: NGFR

Protein Name: Tumor necrosis factor receptor superfamily member 16

Molecular Weight: 45 kDa

Gene ID: 4804

OMIM: 162010

UniProt: P08138

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding