Serotonin Receptor 4 antibody (AA 21-70)

Catalog No. ABIN1534246

The Rabbit Polyclonal anti-Serotonin Receptor 4 antibody is suitable to detect Serotonin Receptor 4 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF and IHC.

Quick Overview for Serotonin Receptor 4 antibody (AA 21-70) (ABIN1534246)

Target: Serotonin Receptor 4 (HTR4)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-Serotonin Receptor 4 Antibody

Binding Specificity: AA 21-70

Purpose: SR-4 Antibody

Specificity: SR-4 Polyclonal Antibody detects endogenous levels of SR-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human 5-HT-4. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Serotonin Receptor 4

Target: Serotonin Receptor 4 (HTR4)

Alternative Name: 5-HT-4

Background:

Synonyms: HTR4, 5-hydroxytryptamine receptor 4, 5-HT-4, 5-HT4, Serotonin receptor 4

Background: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010],

Gene Name: HTR4

Protein Name: 5-hydroxytryptamine receptor 4

Molecular Weight: 43 kDa

Gene ID: 3360

OMIM: 602164

UniProt: Q13639

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, S100 Proteins