CELSR2 antibody (AA 2781-2830)

Catalog No. ABIN1534327

The Rabbit Polyclonal anti-CELSR2 antibody is suitable to detect CELSR2 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for CELSR2 antibody (AA 2781-2830) (ABIN1534327)

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELSR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CELSR2 Antibody

Binding Specificity: AA 2781-2830

Purpose: CDHF10 Antibody

Specificity: CDHF10 Polyclonal Antibody detects endogenous levels of CDHF10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CELSR2. AA range:2781-2830

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CELSR2

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Alternative Name: CELSR2

Background:

Synonyms: CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3, Cadherin EGF LAG seven-pass G-type receptor 2, Cadherin family member 10, Epidermal growth factor-like protein 2, EGF-like protein 2, Flamingo homolog 3, Multiple epidermal growth factor-like domains

Background: The protein encoded byThis gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins, a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: CELSR2

Protein Name: Cadherin EGF LAG seven-pass G-type receptor 2

Molecular Weight: 317 kDa

Gene ID: 1952

OMIM: 604265

UniProt: Q9HCU4