SPINT2 antibody (C-Term)

Catalog No. ABIN1536879

Product Details anti-SPINT2 Antibody

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Binding Specificity: AA 222-251, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINT2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPINT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human SPINT2.

Clone: RB30605

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SPINT2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for SPINT2

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Alternative Name: SPINT2 (SPINT2 Products)

Synonyms: HAI-2 antibody, Pb antibody, DIAR3 antibody, HAI2 antibody, Kop antibody, PB antibody, AL024025 antibody, C76321 antibody, serine peptidase inhibitor, Kunitz type, 2 antibody, serine peptidase inhibitor, Kunitz type 2 antibody, serine protease inhibitor, Kunitz type 2 antibody, Spint2 antibody, SPINT2 antibody

Background: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 28228

Gene ID: 10653

NCBI Accession: NP_001159575, NP_066925

UniProt: O43291