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PDZD3 antibody (AA 258-285)

PDZD3 Reactivity: Human WB Host: Rabbit Polyclonal RB37960 unconjugated
Catalog No. ABIN1538201
  • Target See all PDZD3 Antibodies
    PDZD3 (PDZ Domain Containing 3 (PDZD3))
    Binding Specificity
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-285
    Reactivity
    • 30
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 25
    • 5
    Rabbit
    Clonality
    • 27
    • 3
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This PDZD3 antibody is un-conjugated
    Application
    • 25
    • 21
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.
    Clone
    RB37960
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDZD3 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    PDZD3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    PDZD3 (PDZ Domain Containing 3 (PDZD3))
    Alternative Name
    PDZD3 (PDZD3 Products)
    Synonyms
    RGD1559807 antibody, zgc:194812 antibody, IKEPP antibody, NHERF4 antibody, PDZK2 antibody, NaPi-Cap2 antibody, Pdzk2 antibody, PDZ domain containing 3 antibody, PDZ domain containing 3b antibody, Pdzd3 antibody, pdzd3b antibody, PDZD3 antibody
    Background
    Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).
    Gene ID
    79849
    NCBI Accession
    NP_001161940, NP_079067
    UniProt
    Q86UT5
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