Mps1 antibody (N-Term)

Catalog No. ABIN1539428

Product Details anti-Mps1 Antibody

Target: Mps1 (TTK)

Binding Specificity: AA 6-35, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mps1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human TTK.

Clone: RB36754

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TTK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK (TTK Products)

Synonyms: CT96 antibody, ESK antibody, MPH1 antibody, MPS1 antibody, MPS1L1 antibody, PYT antibody, AL022661 antibody, Esk1 antibody, Mps1 antibody, esk antibody, mps1 antibody, ncp antibody, Ttk protein kinase antibody, TTK protein kinase antibody, ttk protein kinase antibody, Ttk antibody, TTK antibody, ttk antibody

Background: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Molecular Weight: 97072

Gene ID: 7272

NCBI Accession: NP_001160163, NP_003309

UniProt: P33981