CYP1A2 antibody (AA 255-282)

Catalog No. ABIN1539921

The Mouse Monoclonal anti-CYP1A2 antibody (Clone 499CT13-2-2) (ABIN1539921) specifically detects CYP1A2 in WB. The antibody is reactive with Human samples.

Quick Overview for CYP1A2 antibody (AA 255-282) (ABIN1539921)

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP1A2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 499CT13-2-2

Product Details anti-CYP1A2 Antibody

Binding Specificity: AA 255-282

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CYP1A2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from human CYP1A2.

Isotype: IgG3

Application Details

Application Notes: WB: 1:500~2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CYP1A2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Alternative Name: CYP1A2

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Molecular Weight: 58407

Gene ID: 1544

NCBI Accession: NP_000752

UniProt: P05177