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BIRC7 antibody (C-Term)
BIRC7
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BIRC7 Antibody
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Target
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BIRC7
(Baculoviral IAP Repeat-Containing 7 (BIRC7))
Binding Specificity
All epitopes for BIRC7 antibodies
C-Term
Reactivity
All reactivities for BIRC7 antibodies
Human
Host
All hosts for BIRC7 antibodies
Rabbit
Clonality
All clonalities for BIRC7 antibodies
Polyclonal
Conjugate
All conjugates for BIRC7 antibodies
This BIRC7 antibody is un-conjugated
Application
All applications for BIRC7 antibodies
Western Blotting (WB)
Specificity
The antibody detects a band at ~33 kDa and a weaker band at 30 kDa, corresponding to Livin α and β.
Purification
Peptide affinity purified
Immunogen
Synthetic peptide surrounding amino acid near the C- terminus of the long form of human Livin
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Alternatives
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Application Details
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Application Notes
Western Blot: 2-6 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target Details for BIRC7
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Target
BIRC7
(Baculoviral IAP Repeat-Containing 7 (BIRC7))
Alternative Name
BIRC7 / LIVIN (BIRC7 Products )
Synonyms
KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
Background
Livin is a novel member in the IAP (inhibitor of apoptosis) protein family. Livin contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-α and Livin-β. Transfection of Livin protected cells from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6. Livin directly react with several caspases including Caspase-3, -7, and -9, and it inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c and ATP.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50
Gene ID
79444
NCBI Accession
NP_071444
UniProt
Q96CA5
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